MOUSE :: F2 :: C3H/HeJ.Apoe-/- x C57BL/6J.Apoe-/- F2

T.         C3H/HeJ.Apoe-/- x C57BL/6JApoe -/- F2

1.         Mice (S. Wang)
2.         Diets (S. Wang)
3.         Genotyping (S. Wang)
4.         Expression arrays, liver, brain, adipose, muscle (S. Wang)
5.         Atherosclerosis (S. Wang)
6.         Tissues, weights (S. Wang)
7.         Adipose, NMR (S. Wang)
8.         Plasma lipoproteins (L. Castellani)
9.         QTL analyses, clinical traits (S. Wang)
10.       eQTL analyses (S. Wang)
11.       Bone parameters (C. Farber)

 

The protocols for these studies can be found in the following references:

Wang S, Yehya N, Schadt EE, Wang H, Drake TA, Lusis AJ. Genetic and genomic
analysis of a fat mass trait with complex inheritance reveals marked sex
specificity. PLoS Genet. 2006 Feb;2(2):e15. Epub 2006 Feb 3. PubMed PMID:
16462940.

Yang X, Schadt EE, Wang S, Wang H, Arnold AP, Ingram-Drake L, Drake TA, Lusis
AJ. Tissue-specific expression and regulation of sexually dimorphic genes in
mice. Genome Res. 2006 Aug;16(8):995-1004. Epub 2006 Jul 6. PubMed PMID:
16825664.